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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NDRG3
All Species:
26.36
Human Site:
Y315
Identified Species:
64.44
UniProt:
Q9UGV2
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UGV2
NP_071922.2
375
41409
Y315
Y
F
L
Q
G
M
G
Y
I
P
S
A
S
M
T
Chimpanzee
Pan troglodytes
A5A6K6
357
39342
L297
T
E
A
F
K
Y
F
L
Q
G
M
G
Y
M
A
Rhesus Macaque
Macaca mulatta
XP_001088529
394
42883
Y314
Y
F
V
Q
G
M
G
Y
M
P
S
A
S
M
T
Dog
Lupus familis
XP_865665
366
40058
Y306
Y
F
L
Q
G
M
G
Y
I
P
S
A
S
M
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9QYF9
375
41536
Y315
Y
F
L
Q
G
M
G
Y
I
P
S
A
S
M
T
Rat
Rattus norvegicus
Q6AYR2
375
41488
Y315
Y
F
L
Q
G
M
G
Y
I
P
S
A
S
M
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417315
387
42477
Y315
Y
F
V
Q
G
M
G
Y
I
P
Y
V
Q
L
S
Frog
Xenopus laevis
Q6GQL1
375
41290
Y315
Y
F
V
Q
G
M
G
Y
M
P
S
A
S
M
T
Zebra Danio
Brachydanio rerio
Q5PR98
368
40449
I309
T
E
A
F
K
Y
F
I
Q
G
M
G
Y
M
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O02485
325
35573
E266
N
V
A
D
V
M
Q
E
A
P
D
K
L
A
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
57.5
62.1
90.1
N.A.
96
96.5
N.A.
N.A.
81.6
75.1
54.9
N.A.
N.A.
N.A.
26.1
N.A.
Protein Similarity:
100
71.1
76.1
92.8
N.A.
98.4
98.6
N.A.
N.A.
87.5
86.6
70.6
N.A.
N.A.
N.A.
43.2
N.A.
P-Site Identity:
100
6.6
86.6
100
N.A.
100
100
N.A.
N.A.
60
86.6
6.6
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
6.6
100
100
N.A.
100
100
N.A.
N.A.
80
100
6.6
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
30
0
0
0
0
0
10
0
0
60
0
10
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
0
20
0
0
0
0
0
10
0
0
0
0
0
0
0
% E
% Phe:
0
70
0
20
0
0
20
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
70
0
70
0
0
20
0
20
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
50
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
20
0
0
0
0
0
0
10
0
0
0
% K
% Leu:
0
0
40
0
0
0
0
10
0
0
0
0
10
10
0
% L
% Met:
0
0
0
0
0
80
0
0
20
0
20
0
0
80
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
80
0
0
0
0
0
% P
% Gln:
0
0
0
70
0
0
10
0
20
0
0
0
10
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
60
0
60
0
10
% S
% Thr:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
60
% T
% Val:
0
10
30
0
10
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
70
0
0
0
0
20
0
70
0
0
10
0
20
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _